It used to be that when you got sick, your doctor would come to you. But as medical equipment, expertise and knowledge, and the entire modern healthcare system evolved, we created grand institutions to make granting healthcare to the masses more efficient. That system did us much good—but also comes with much cost. Today, healthcare is dramatically changing once again to embrace new equipment, expertise, and knowledge. In short, it’s leaving the building. Jorge Conde, a16z General Partner on the Bio Fund, argues in this talk (first given at the 2019 Oliver Wyman Health Innovation Summit) that the healthcare system is getting unbundled—and everything from where we get our care to what our medicines will look like to even how we experience symptoms will look very different in the future. The same trends that created the modern healthcare system are now pushing us to a future that might look a lot more like our past.